Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Contributors in Biochemistry

Biochemistry

Allosteric regulation; the modification of binding or catalytic properties of a protein by binding of a regulator at a site distinct from the ligand- or substrate-binding site. Allostery typically ...

allosteric effector

Biology; Biochemistry

A compound that modifies the activity of an enzyme, or its affinity for its substrate, by binding to a site distinct from the active site; a positive effector increases the activity, a negative ...

allosteric regulation

Biology; Biochemistry

The modification of binding or catalytic properties of a protein by attachment of a regulator at a site distinct from the ligand- or substrate-binding site. Allostery typically results in sigmoidal ...

high-energy bond

Biology; Biochemistry

A chemical bond whose hydrolysis results in the generation of ≧30kJ (7kcal) of energy or, if coupled to an energetically unfavorable reaction, can drive that reaction forward. Examples are found in ...

optimal matching hydrophobicity (OMH)

Biology; Biochemistry

A calculated value used to predict conformational similarities of proteins from their amino acid sequences. Numerical values for hydrophobicity, OMHs, are assigned to each amino acid residue to allow ...

area detector

Biology; Biochemistry

An 'electronic film'; a device for measurement of diffracted radiation, e.g. in X-ray crystallographic analysis; detector devices are densely arrayed over a screen and report to a computer the ...

competitive inhibition

Biology; Biochemistry

A form of enzyme inhibition in which the inhibitor competes with the substrate for the enzyme's substrate-binding site. The result is an increase in the K m value while leaving V max unaltered.