19 Terms
Contributors in Genetics
Genetics
Allele frequency
Biology; Genetics
The proportion of chromosomes in a population harboring a specific allele. "Minor allele frequency" typically refers to the less common variant at a biallelic locus and is usually used to refer to ...
Allelic heterogeneity
Biology; Genetics
Common occurrence of multiple mutations in one gene that all result in the same disease or syndrome. As an example, more than 1500 mutations in the cystic fibrosis transmembrane conductance regulator ...
Aneuploidy
Biology; Genetics
Aneuploidy can affect the entire somatic cell population, as in trisomy 21, or it can affect a subset of cells, as in a tumor.
Anticipation
Biology; Genetics
A phenomenon whereby the symptoms of a genetically-based condition appear at an earlier age, or with greater severity, in successive generations. Expansion of short tandem or trinucleotide repeats is ...
Association
Biology; Genetics
A tendency for two characteristics to occur together at non-random frequencies. Note that this is a statistical correlation and does not by itself imply causation.
