30 Terms
Home > Industry/Domain > Biology > Immunology
Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
platelet endothelial cell adhesion molecule (PECAM)
Biology; Immunology
The cell-adhesion molecule PECAM (CD31) is found both on lymphocytes and at endothelial cell junctions. It is believed that CD31–CD31 interactions enable leukocytes to leave blood vessels and enter ...
graft rejection
Biology; Immunology
Tissue and organ grafts between genetically distinct individuals almost always elicit an adaptive immune response that causes graft rejection, the destruction of the grafted tissue by attacking ...
centroblasts
Biology; Immunology
Centroblasts are large, rapidly dividing cells found in germinal centers, and are the cells in which somatic hypermutation is believed to occur. Antibody-secreting and memory B cells derive from ...
gene conversion
Biology; Immunology
In birds and rabbits, immunoglobulin receptor diversity is generated mainly by gene conversion, in which homologous inactive V gene segments exchange short sequences with an active, rearranged ...
12/23 rule
Biology; Immunology
The 12/23 rule states that gene segments of immunoglobulin or T-cell receptors can be joined only if one has a recognition signal sequence with a 12 base pair spacer, and the other has a 23 base pair ...
iccosomes
Biology; Immunology
Iccosomes are small fragments of membrane coated with immune complexes that fragment off the processes of follicular dendritic cells in lymphoid follicles early in a secondary or subsequent antibody ...
confocal fluorescent microscopy
Biology; Immunology
In confocal fluorescent microscopy, it is possible to use optics to produce images at very high resolution by having two origins of fluorescent light that come together only at one plane of a thicker ...
