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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

membrane cofactor of proteolysis

Biology; Immunology

Membrane cofactor of proteolysis (MCP or CD46) is a host-cell membrane protein that acts in conjunction with factor I to cleave C3b to its inactive derivative iC3b and thus prevent convertase ...

plasma cells

Biology; Immunology

Plasma cells are terminally differentiated B lymphocytes and are the main antibody-secreting cells of the body. They are found in the medulla of the lymph nodes, in splenic red pulp, and in bone ...

linkage disequilibrium

Biology; Immunology

Alleles at linked loci within the major histocompatibility complex are said to be in linkage disequilibrium if they are inherited together more frequently than predicted from their individual ...

c-Kit

Biology; Immunology

The cell-surface receptor c-Kit, present on developing B cells and other developing white blood cells, binds to the stem cell factor on bone marrow stromal cells. Kit has protein tyrosine kinase ...

terminal complement components,

Biology; Immunology

The complement system can be activated directly or by antibody, but both pathways converge with the activation of the terminal complement components, which may assemble to form the membraneattack ...

transgenesis

Biology; Immunology

Foreign genes can be placed in the mouse genome by transgenesis. This generates transgenic mice that are used to study the function of the inserted gene, or transgene, and the regulation of its ...

MadCAM-1

Biology; Immunology

MadCAM-1 is the mucosal cell adhesion molecule-1 or mucosal addressin that is recognized by the lymphocyte surface proteins L-selectin and VLA-4, allowing specific homing of lymphocytes to mucosal ...

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