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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

immunophilins

Biology; Immunology

Immunophilins are proteins with peptidyl-prolyl cis–trans isomerase activity that bind the immunosuppressive drugs cyclosporin A, tacrolimus, and rapamycin.

killer activatory receptors

Biology; Immunology

Killer activatory receptors (KARs) are cell-surface receptors on NK cells or cytotoxic T cells; they are receptors that can activate killing by these cells.

lymphotoxin

Biology; Immunology

Lymphotoxin (LT) is also known as tumor necrosis factor-β (TNF-β), a cytokine secreted by inflammatory CD4T cells that is directly cytotoxic for some cells.

scatchard analysis

Biology; Immunology

Scatchard analysis is a mathematical analysis of equilibrium binding that allows the affinity and valence of a receptor–ligand interaction to be determined.

smallpox

Biology; Immunology

Smallpox is an infectious disease, caused by the virus variola, that once killed at least 10% of infected people. It has now been eradicated by vaccination.

immunoglobulin D (IgD)

Biology; Immunology

IgD is the class of immunoglobulin characterized by δ heavy chains. It appears as surface immunoglobulin on mature naive B cells but its function is unknown.

immunodeficiency diseases

Biology; Immunology

Immunodeficiency diseases are a group of inherited or acquired disorders in which some aspect or aspects of host defense are absent or functionally defective.

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