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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

paracortical area

Biology; Immunology

The paracortical area, or paracortex, is the T-cell area of lymph nodes, lying just below the follicular cortex, which is primarily composed of B cells.

host-versus-graft disease

Biology; Immunology

Host-versus-graft disease (HVGD) is another name for the allograft rejection reaction. The term is used mainly in relation to bone marrow transplantation.

kupffer cells

Biology; Immunology

Kupffer cells are phagocytes lining the hepatic sinusoids; they remove debris and dying cells from the blood, but are not known to elicit immune responses.

lysosomes

Biology; Immunology

Lysosomes are acidified organelles that contain many degradative hydrolytic enzymes. Material taken up into endosomes is eventually delivered to lysosomes.

hematopoietic lineage

Biology; Immunology

A hematopoietic lineage is any developmental series of cells that derives from hematopoietic stem cells and results in the production of mature blood cells.

CD40 ligand

Biology; Immunology

B-cell growth is triggered in part by the binding of CD40 ligand, also known as CD154, expressed on activated helper T cells, to CD40 on the B-cell surface.

DNA microarrays

Biology; Immunology

DNA microarrays are created by placing a different DNA on a small part of a microchip, and using them to assess RNA expression in normal or malignant cells.

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