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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
calreticulin
Biology; Immunology
Calreticulin is the molecular chaperone that binds initially to MHC class I, MHC class II, and other proteins that contain immunoglobulin-like domains, such as the T-cell and B-cell antigen ...
haptens
Biology; Immunology
Haptens are molecules that can bind antibody but cannot by themselves elicit an adaptive immune response. Haptens must be chemically linked to protein carriers to elicit antibody and T-cell ...
effector mechanisms
Biology; Immunology
Effector mechanisms are those processes by which pathogens are destroyed and cleared from the body. Innate and adaptive immune responses use most of the same effector mechanisms to eliminate ...
T-cell hybrids
Biology; Immunology
T-cell hybrids are formed by fusing an antigen-specific, activated T cell with a T-cell lymphoma. The hybrid cells bear the receptor of the specific T-cell parent and grow in culture like the ...
TH2 cells
Biology; Immunology
TH2 cells are a subset of CD4 T cells that are characterized by the cytokines they produce. They are mainly involved in stimulating B cells to produce antibody, and are often called helper CD4 T ...
variability
Biology; Immunology
The variability of a protein is a measure of the difference between the amino acid sequences of different variants of that protein. The most variable proteins known are antibodies and T-cell ...
nonproductive rearrangements
Biology; Immunology
When T- and B-cell receptor gene segments rearrange, they often form nonproductive rearrangements that cannot encode a protein because the coding sequences are in the wrong translational reading ...
