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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

lentiviruses

Biology; Immunology

Lentiviruses are a group of retroviruses that include the human immunodeficiency virus, HIV-1. They cause disease after a long incubation period and can take years to become apparent.

paroxysmal nocturnal hemoglobinuria

Biology; Immunology

Paroxysmal nocturnal hemoglobinuria (PNH) is a disease in which complement regulatory proteins are defective, so that complement activation leads to episodes of spontaneous hemolysis.

cowpox

Biology; Immunology

Cowpox is the common name of the disease produced by vaccinia virus, used by Edward Jenner in the successful vaccination against smallpox, which is caused by the related variola virus.

experimental allergic encephalomyelitis

Biology; Immunology

Experimental allergic encephalomyelitis (EAE) is an inflammatory disease of the central nervous system that develops after mice are immunized with neural antigens in a strong adjuvant.

germline configuration

Biology; Immunology

Immunoglobulin and T-cell receptor genes are said to be in the germline configuration in the DNA of germ cells and in all somatic cells in which somatic recombination has not occurred.

scavenger receptors

Biology; Immunology

Scavenger receptors on macrophages and other cells bind to numerous ligands and remove them from the blood. The Kupffer cells in the liver are particularly rich in scavenger receptors.

decay-accelerating factor

Biology; Immunology

The decay-accelerating factor (DAF or CD55) is a cell-surface molecule that protects cells from lysis by complement. Its absence causes the disease paroxysmal nocturnal hemoglobinuria.

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