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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

C5a receptor

Biology; Immunology

The receptor for the C5a fragment of complement, the C5a receptor, is a seven-transmembrane spanning receptor that couples to a heterotrimeric G protein. Similar receptors bind to C3a and C4a.

recessive lethal gene

Biology; Immunology

A recessive lethal gene encodes a protein that is needed for the human or animal to develop to adulthood; when both copies are defective, the human or animal dies in utero or early after birth.

homeostasis

Biology; Immunology

Homeostasis is a generic term describing the status of physiological normality. In the case of lymphocytes, homeostasis refers to an uninfected individual who has normal numbers of lymphocytes.

tapasin

Biology; Immunology

Tapasin, or the TAP-associated protein, is a key molecule in the assembly of MHC class I molecules; a cell deficient in this protein has only unstable MHC class I molecules on the cell surface.

B-lymphocyte stimulator (BLyS)

Biology; Immunology

BLyS is a secreted member of the TNF family of cytokines. It is secreted by T cells and plays critical roles in germinal center and plasma-cell formation, and possibly dendritic-cell maturation.

serotype

Biology; Immunology

Different strains of bacteria and other pathogens can sometimes be distinguished by their serotype, the ability of an immune serum to agglutinate or lyse some strains of bacteria and not others.

TH1 cells

Biology; Immunology

TH1 cells are a subset of CD4 T cells that are characterized by the cytokines they produce. They are mainly involved in activating macrophages, and are sometimes called inflammatory CD4 T cells.

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