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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
MIC molecules
Biology; Immunology
MIC molecules are MHC class I-like molecules that are expressed in the gut under conditions of stress and are encoded within the class I region of the human MHC. They are not found in mice.
respiratory burst
Biology; Immunology
When neutrophils and macrophages take up opsonized particles, this triggers a metabolic change in the cell called the respiratory burst. It leads to the production of a number of mediators.
immunoblotting
Biology; Immunology
Immunoblotting is a common technique in which proteins separated by gel electrophoresis are blotted onto a nitrocellulose membrane and revealed by the binding of specific labeled antibodies.
stem-cell factor
Biology; Immunology
Stem-cell factor (SCF) is a transmembrane protein on bone marrow stromal cells that binds to c-Kit, a signaling receptor carried on developing B cells and other developing white blood cells.
MHC class II compartment
Biology; Immunology
The MHC class II compartment (MIIC) is a site in the cell where MHC class II molecules accumulate, encounter HLA-DM, and bind antigenic peptides, before migrating to the surface of the cell.
Rev protein
Biology; Immunology
The Rev protein is the product of the rev gene of the human immuno-deficiency virus (HIV). The Rev protein promotes the passage of viral RNA from nucleus to cytoplasm during HIV replication.
tissue-specific autoimmune disease
Biology; Immunology
Some autoimmune diseases attack particular tissues, such as the β cell in the islets of Langerhans in autoimmune diabetes mellitus; such diseases are called tissue-specific autoimmune disease.
