6 Terms
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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
prednisone
Biology; Immunology
Prednisone is a synthetic steroid with potent anti-inflammatory and immunosuppressive activity used in treating acute graft rejection, autoimmune disease, and lymphoid tumors.
stromal cells
Biology; Immunology
The development of B lymphocytes and T lymphocytes occurs in association with stromal cells, which provide various soluble and cell-bound signals to the developing lymphocyte.
signal joint
Biology; Immunology
A signal joint is formed by the precise joining of recognition signal sequences in the process of somatic recombination that generates T-cell receptor and immunoglobulin genes.
antagonist peptides
Biology; Immunology
Antagonist peptides are peptides, usually closely related in sequence to an agonist peptide, that inhibit the response of a cloned T-cell line specific for the agonist peptide.
inducible costimulator (ICOS)
Biology; Immunology
ICOS is a CD28-related protein that is induced on activated T cells and can enhance T-cell responses. It binds a ligand known as LICOS, which is distinct from the B7 molecules.
polygenic
Biology; Immunology
The major histocompatibility complex is both polygenic, containing several loci encoding proteins of identical function, and polymorphic, having multiple alleles at each locus.
nude
Biology; Immunology
The nude mutation of mice produces hairlessness and defective formation of the thymic stroma, so that nude mice, which are homozygous for this mutation, have no mature T cells.
