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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
death domains
Biology; Immunology
Death domains were originally defined in proteins encoded by genes involved in programmed cell death or apoptosis, and are now known to be involved in protein–protein interactions.
acute-phase response
Biology; Immunology
The acute-phase response is a change in the blood that occurs during early phases of an infection. It includes the production of acute-phase proteins and also of cellular elements.
Fcε receptor
Biology; Immunology
The high-affinity Fcε receptor (FcεRI) on the surface of mast cells and basophils binds free IgE. When antigen binds this IgE and cross-links FcεRI, it causes mast-cell activation.
receptor-mediated endocytosis
Biology; Immunology
Receptor-mediated endocytosis is the internalization into endosomes of molecules bound to cell-surface receptors. Antigens bound to B-cell receptors are internalized by this process.
kinin system
Biology; Immunology
The kinin system is an enzymatic cascade of plasma proteins that is triggered by tissue damage to produce several inflammatory mediators, including the vasoactive peptide bradykinin.
B-cell co-receptor
Biology; Immunology
A complex of CD19, TAPA-1, and CR2 makes up the B-cell co-receptor; co-ligation of this complex with the B-cell antigen receptor increases responsiveness to antigen by about 100-fold.
Goodpasture’s syndrome
Biology; Immunology
Goodpasture’s syndrome is an autoimmune disease in which autoantibodies against basement membrane or type IV collagen are produced and cause extensive vasculitis. It is rapidly fatal.
