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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
arthus reaction
Biology; Immunology
The Arthus reaction is a skin reaction in which antigen is injected into the dermis and reacts with IgG antibodies in the extracellular spaces, activating complement and phagocytic cells to produce a ...
electrophoresis
Biology; Immunology
Electrophoresis is the movement of molecules in a charged field. In immunology, many forms of electrophoresis are used to separate molecules, especially protein molecules, to determine their charge, ...
farmer’s lung
Biology; Immunology
Farmer’s lung is a hypersensitivity disease caused by the interaction of IgG antibodies with large amounts of an inhaled allergen in the alveolar wall of the lung, causing alveolar wall inflammation ...
wheal-and-flare reaction
Biology; Immunology
When small amounts of allergen are injected into the dermis of an allergic individual, a wheal-and-flare reaction is observed. This consists of a raised area of skin containing fluid and a spreading, ...
mannose-associated serine protease 1 (MASP-1)
Biology; Immunology
The components of the MB-lectin pathway of complement activation include two serine proteases, MASP-1 and MASP-2, that bind to mannan-binding lectin and play the same role in cleaving C4 as do C1r ...
nuclear factor kappa B (NFκB)
Biology; Immunology
The transcription factor called NFκB is made up of two chains of 50 kDa and 65 kDa. It is found under normal circumstances in the cytosol, where it is bound to a third chain called IκB, which is an ...
TNF receptor
Biology; Immunology
There are several members of the TNF receptor (TNFR) family. Some lead to apoptosis of the cell on which they are expressed (TNFR-I, II, Fas), while others lead to activation (CD40, 4-1BB). All of ...
