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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
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Immunology
Hodgkin’s disease
Biology; Immunology
Hodgkin’s disease is an immune system tumor characterized by large cells called Reed-Sternberg cells, which derive from mutated B-lineage cells. It exists in at least two polar forms, Hodgkin’s ...
systemic lupus erythematosus
Biology; Immunology
Systemic lupus erythematosus (SLE) is an autoimmune disease in which autoantibodies against DNA, RNA, and proteins associated with nucleic acids form immune complexes that damage small blood vessels, ...
recombination activating gene (RAG-1)
Biology; Immunology
The recombination activating genes RAG-1 and RAG-2 encode the proteins RAG-1 and RAG-2, which are critical to receptor gene rearrangement. Mice lacking either of these genes cannot form receptors and ...
staphylococcal enterotoxins
Biology; Immunology
Staphylococcal enterotoxins (SEs) cause food poisoning and also stimulate many T cells by binding to MHC class II molecules and the Vb domain of certain T-cell receptors; the staphylococcal ...
TH3 cell
Biology; Immunology
The term TH3 cell has been used to describe unique cells that produce mainly transforming growth factor-β in response to antigen; they develop predominantly in the mucosal immune response to antigens ...
mitogen-activated protein kinases
Biology; Immunology
Mitogen-activated protein kinases (MAP kinases) are kinases that become phosphorylated and activated on cellular stimulation by a variety of ligands, and lead to new gene expression by ...
multiple myeloma
Biology; Immunology
Multiple myeloma is a tumor of plasma cells, almost always first detected as multiple foci in bone marrow. Myeloma cells produce a monoclonal immunoglobulin, called a myeloma protein, that is ...
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