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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
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Immunology
Hashimoto’s thyroiditis
Biology; Immunology
Hashimoto’s thyroiditis is an autoimmune disease characterized by persistent high levels of antibody against thyroid-specific antigens. These antibodies recruit NK cells to the tissue, leading to ...
Langerhans’ cells
Biology; Immunology
Langerhans’ cells are phagocytic dendritic cells found in the epidermis. They can migrate from the epidermis to regional lymph nodes via the afferent lymphatics. In the lymph node they differentiate ...
peripheral
Biology; Immunology
Peripheral or secondary lymphoid organs are the lymph nodes, spleen, and mucosal-associated lymphoid tissues, in which immune responses are induced, as opposed to the central lymphoid organs, in ...
protectin
Biology; Immunology
Protectin (CD59) is a cell-surface protein that protects host cells from being damaged by complement. It inhibits the formation of the membrane-attack complex by preventing the binding of C8 and C9 ...
Weibel–Palade bodies
Biology; Immunology
Weibel–Palade bodies are granules within endothelial cells that contain P-selectin. Activation of the endothelial cell by mediators such as histamine and C5a leads to rapid translocation of ...
macrophage activation
Biology; Immunology
Resting macrophages will not destroy certain intracellular bacteria unless the macrophage is activated by a T cell. Macrophage activation is important in controlling infection and also causes damage ...
cluster of differentiation 4 (CD4)
Biology; Immunology
The cell-surface protein CD4 is important for recognition by the T-cell receptor of antigenic peptides bound to MHC class II molecules. It acts as a co-receptor by binding to the lateral face of the ...
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