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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
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Immunology
first set rejection
Biology; Immunology
When tissue or organ grafts are placed in an unmatched recipient, they are rejected by a first set rejection, which is an immune response by the host against foreign antigens in the graft. Cf. second ...
cross-matching
Biology; Immunology
Cross-matching is used in blood typing and histocompatibility testing to determine whether donor and recipient have antibodies against each other’s cells that might interfere with successful ...
human leukocyte antigen (HLA)
Biology; Immunology
HLA is the genetic designation for the human MHC. Individual loci are designated by upper-case letters, as in HLA-A, and alleles are designated by numbers, as in HLA-A*0201.
fungi
Biology; Immunology
Fungi are single-celled and multicellular eukaryotic organisms, including the yeasts and molds, that can cause a variety of diseases. Immunity to fungi is complex and involves both humoral and ...
cluster of differentiation 8 (CD8)
Biology; Immunology
The cell-surface protein CD8 is important for recognition by the T-cell receptor of antigenic peptides bound to MHC class I molecules. It acts as a co-receptor by binding to the lateral face of MHC ...
reverse transcriptase–polymerase chain reaction
Biology; Immunology
The reverse transcriptase–polymerase chain reaction (RT-PCR) is used to amplify RNA sequences. The enzyme reverse transcriptase is used to convert an RNA sequence into a cDNA sequence, which is then ...
inositol trisphosphate
Biology; Immunology
When inositol phospholipid is cleaved by phospholipase C-γ, it yields inositol trisphosphateIP3 and diacylglycerol. Inositol trisphosphate releases calcium ions from intracellular stores in the ...