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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
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Immunology
high endothelial venules
Biology; Immunology
High endothelial venules (HEVs) are specialized venules found in lymphoid tissues. Lymphocytes migrate from blood into lymphoid tissues by attaching to and migrating across the high endothelial cells ...
western blotting
Biology; Immunology
In Western blotting, a mixture of proteins is separated, usually by gel electrophoresis and transferred by blotting to a nitrocellulose membrane; labeled antibodies are then used as probes to detect ...
intracellular cytokine staining
Biology; Immunology
Staining for cytokines in cells that produce them can be achieved by permiablizing the cell and reacting it with a labelled fluorescent anti-cytokine antibody. This procedure is called intracellular ...
insulin-dependent diabetes mellitus
Biology; Immunology
In insulin-dependent diabetes mellitus (IDDM), the β cells of the pancreatic islets of Langerhans are destroyed so that no insulin is produced. The disease is believed to result from an autoimmune ...
C domains
Biology; Immunology
The constant regions of the polypeptide chains of immunoglobulin molecules are made up of one or more constant domains or C domains of similar structure; each immunoglobulin chain also has a single ...
V domain
Biology; Immunology
The variable region of the polypeptide chains of an immunoglobulin or T-cell receptor is composed of a single N-terminal V domain. Paired V domains form the antigen-binding sites of immunoglobulins ...
pro-B cells
Biology; Immunology
During B-cell development, pro-B cells are cells that have displayed B-cell surface marker proteins but have not yet completed heavy-chain gene rearrangement. They are divided into early pro-B cells ...