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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
calnexin
Biology; Immunology
The protein calnexin is an 88 kDa protein found in the endoplasmic reticulum. It binds to partly folded members of the immunoglobulin superfamily of proteins and retains them in the endoplasmic ...
MHC haplotype
Biology; Immunology
MHC genes are inherited in most cases as an MHC haplotype, the set of genes in a haploid genome inherited from one parent. Thus, if the parents are designated as ab and cd, then the offspring are ...
MHC:peptide tetramers
Biology; Immunology
The development of MHC:peptide tetramers held together by fluorescent streptavidin, which has four binding sites for the biotin attached to the tail of the MHC molecule, has made it possible to stain ...
B-cell lymphoma 2 (Bcl-2)
Biology; Immunology
The protein known as Bcl-2 protects cells from apoptosis by binding to the mitochondrial membrane. It is encoded by the bcl-2 gene, which was discovered at the breakpoint of an oncogenic chromosomal ...
L-selectin
Biology; Immunology
L-selectin is an adhesion molecule of the selectin family found on lymphocytes. L-selectin binds to CD34 and GlyCAM-1 on high endothelial venules to initiate the migration of naive lymphocytes into ...
common γ chain
Biology; Immunology
The common γ chain (γc) is a transmembrane polypeptide chain (CD132) that is common to a subgroup of class I cytokine receptors. It plays a key role in the intracellular signaling mediated by these ...
agonist peptides
Biology; Immunology
Agonist peptides are peptide antigens that activate their specific T cells, inducing them to make cytokines and to proliferate. They are thought to differ from antagonist peptides by their ability to ...
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