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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

transporter antigen peptide 1 (TAP1)

Biology; Immunology

TAP1 and TAP2 (transporters associated with antigen processing) are ATP-binding cassette proteins involved in transporting short peptides from the cytosol into the lumen of the endoplasmic reticulum, ...

X-linked hyper IgM syndrome

Biology; Immunology

X-linked hyper IgM syndrome is a disease in which little or no IgG, IgE, or IgA antibody is produced and even IgM responses are deficient, but serum IgM levels are normal to high. It is due to a ...

MHC molecules

Biology; Immunology

MHC molecules is the general name given to the highly polymorphic glycoproteins encoded by MHC class I and MHC class II genes, which are involved in the presentation of peptide antigens to T cells. ...

B-cell antigen receptor

Biology; Immunology

The B-cell antigen receptor, or B-cell receptor (BCR), is the cell-surface receptor of B cells for specific antigen. It is composed of a transmembrane immunoglobulin molecule associated with the ...

GlyCAM-1

Biology; Immunology

GlyCAM-1 is a mucinlike molecule found on the high endothelial venules of lymphoid tissues. It is an important ligand for the L-selectin molecule expressed on naive lymphocytes, directing these cells ...

antigen:antibody complexes

Biology; Immunology

Antigen:antibody complexes are noncovalently associated groups of antigen and antibody molecules that can vary in size from small soluble complexes to large insoluble complexes that precipitate out ...

X chromosome-linked immune deficiency gene (xid)

Biology; Immunology

Mice with mutations in the btk gene have a deficiency in making antibodies, especially in primary responses. These mice are called xid, for X-linked immunodeficiency, the mouse equivalent of X-linked ...

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