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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

collectins

Biology; Immunology

Collectins are a structurally related family of calcium-dependent sugar-binding proteins or lectins containing collagen-like sequences. An example is mannan-binding lectin.

immunosuppressive drugs

Biology; Immunology

Compounds that inhibit adaptive immune responses are called immunosuppressive drugs. They are used mainly in the treatment of graft rejection and severe autoimmune disease.

receptor-associated tyrosine kinases

Biology; Immunology

The antigen receptors of lymphocytes are associated with receptor-associated tyrosine kinases, mainly of the Src family, which bind to receptor tails via their SH2 domains.

mantle zone

Biology; Immunology

The follicular mantle zone is a rim of B lymphocytes that surrounds lymphoid follicles. The precise nature and role of mantle zone lymphocytes have not yet been determined.

cooperativity

Biology; Immunology

Two binding sites are said to demonstrate cooperativity in binding to their ligand when the binding of ligand to one site enhances the binding of ligand to the second site.

oncogenes

Biology; Immunology

Oncogenes are genes involved in regulating cell growth. When these genes are defective in structure or expression, they can cause cells to grow continuously to form a tumor.

follicles

Biology; Immunology

Peripheral lymphoid tissues, such as lymph nodes and Peyer’s patches, contain large areas of B cells called follicles, which are organized around follicular dendritic cells.

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