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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

immunoglobulins

Biology; Immunology

All antibody molecules belong to a family of plasma proteins called immunoglobulins (Ig). Membrane-bound immunoglobulin serves as the specific antigen receptor on B lymphocytes.

ascertainment artifact

Biology; Immunology

Ascertainment artifact refers to data that seem to demonstrate some finding, but fail to do so because they are collected from a population that is selected in a biased fashion.

lymphocyte-specific protein tyrosine kinase (Lck)

Biology; Immunology

The tyrosine kinase Lck associates most strongly with the cytoplasmic tails of CD4 and CD8. It plays a central role in signal transduction and activation of the T-cell receptor.

antigen-capture assay

Biology; Immunology

In an antigen-capture assay, the antigen binds to a specific antibody, and its presence is detected by a second antibody that must be labeled and directed at a different epitope.

edema

Biology; Immunology

In immunology, edema is the swelling caused by the entry of fluid and cells from the blood into the tissues, which is one of the cardinal features of the process of inflammation.

single-positive thymocytes

Biology; Immunology

During T-cell maturation in the thymus, mature T cells are detected by the expression of either the CD4 or the CD8 co-receptor and are therefore called single-positive thymocytes.

mouse mammary tumor virus

Biology; Immunology

Mouse mammary tumor virus (MMTV) is a retrovirus that encodes a viral superantigen; integrated copies of related viruses encode the endogenous superantigens known as Mls antigens.

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