Molecular biology

Molecular biology

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Molecular biology

truncation

Biology; Biochemistry

Elimination of the N- or C-terminal portion of a protein by proteolysis or manipulation of the structural gene, or premature termination of protein elongation due to the presence of a termination ...

Removal of carbon dioxide from a carboxylic acid that is facilitated by oxidation of the α-carbon (α-oxidative decarboxylation, e.g. the pyruvate dehydrogenase reaction) or the β-carbon (β-oxidative ...

transformation

Biology; Biochemistry

The process by which a cell line, that can normally be expected to undergo a limited number of cell divisions before death, becomes immortal; also the process by which isolated foreign DNA is ...

affinity chromatography

Biology; Biochemistry

The separation of soluble macromolecules by use of a stationary phase that is designed to interact specifically with, and thus retard the elution of, the desired material; e.g. a hapten attached to a ...

traffic ATPase

Biology; Biochemistry

A class of transmembrane transporters that includes the cystic fibrosis transmembrane regulator (CFTR) and transporters responsible for multidrug resistance. Transport is coupled to ATP hydrolysis ...

Anfinsen cage

Biology; Biochemistry

A proposed model for chaperone-assisted protein folding in which a chaperone, GroEL for instance, provides an environment in which a denatured protein can unfold and correctly refold, undisturbed by ...

medium-chain fatty acid

Biology; Biochemistry

A fatty acid with a skeleton of 4-12 carbon atoms. Those with fewer carbon atoms are short-chain fatty acids; those with more (up to 20 carbon atoms) are long-chain fatty acids; and those with ...