Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

A technique for electrophoresis of single samples in an open-ended tube. The polyacrylamide stationary phase is polymerized in situ. During electrophoresis the ends of the tube are immersed in upper ...

combinatorial

Biology; Biochemistry

Descriptive of procedures or processes that generate a diversity of molecules (e.g. nucleic acid or protein sequences; related chemical structures) that can be screened for a desired property. The ...

isotope effect

Biology; Biochemistry

The effect on kinetics of the substitution of one isotope for another in a bond that must be broken in a rate-limiting step (primary isotope effect); especially prominent in the case of cleavage of a ...

electron spin resonance (ESR)

Biology; Biochemistry

Also known as electron paramagnetic resonance (EPR); a magnetic resonance technique that detects and characterizes the environment of a moiety that contains an unpaired electron by the energy that is ...

rotational catalysis

Biology; Biochemistry

A proposed partial mechanism of ATP synthase in which a transmembrane ion channel, which is a hexamer composed of a ring of alternating and subunits, in which a single subunit rotates, binding ADP ...

triplex-forming oligonucleotide (TFO)

Biology; Biochemistry

An oligonucleotide that recognizes a specific dsDNA sequence. Designed to affect the expression of a specific gene, it lies in the major groove of the double helix and forms Hoogstein base pairs with ...

dirigent

Biology; Biochemistry

A protein, itself devoid of catalytic activity, taht directs the regio- and stereo-selective course of an enzymic reaction, e.g. the exclusive synthesis by an oxidase of (+)-pinoresinal from two ...