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Molecular biology
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Molecular biology
ataxia telangiectasia mutated
Biology; Biochemistry
Ataxia telangiectasia mutated (ATM) is a protein kinase enzyme that phosphorylates regions of chromatin in DNA following double-stranded breaks (DSBs). Mutations in ATM cause the neurodegenerative ...
single-molecule
Biology; Biochemistry
Descriptive of the enzyme kinetics, or more generally the dynamics of molecules such as enzymes, ion chanels, molecular motors, etc. studied in isolation (e.g. by atomic force or fluorescence ...
aggresome
Biology; Biochemistry
A cytological inclusion in cells that is composed of damaged or mis-folded protein molecules, often following heat stress. Presumably amount of protein in an aggresome is too large to be handled by ...
hairpin loop
Biology; Biochemistry
A region in a single polynucleotide strand containing adjacent complementary sequences that allows the polynucleotide to fold back upon itself and form a double-stranded section, as in the cloverleaf ...
Fresco-Alberts-Doty model
Biology; Biochemistry
A region in a single polynucleotide strand containing adjacent complementary sequences that allows the polynucleotide to fold back upon itself and form a double-stranded section, as in the cloverleaf ...
autoradiography
Biology; Biochemistry
A technique for visualization of radioactivity in histological preparations, paper chromatograms or slab gels from electrophoresis by overlaying the surface with X-ray film and allowing the radiation ...
twisting number (T)
Biology; Biochemistry
A topological property of double-stranded DNA; the number of turns one DNA strand makes around the other; the number of paired bases in a DNA molecule divided by 10; equal to the linking number minus ...
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