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Molecular biology

Contributors in Molecular biology

Molecular biology

ataxia telangiectasia mutated

Biology; Biochemistry

Ataxia telangiectasia mutated (ATM) is a protein kinase enzyme that phosphorylates regions of chromatin in DNA following double-stranded breaks (DSBs). Mutations in ATM cause the neurodegenerative ...

single-molecule

Biology; Biochemistry

Descriptive of the enzyme kinetics, or more generally the dynamics of molecules such as enzymes, ion chanels, molecular motors, etc. studied in isolation (e.g. by atomic force or fluorescence ...

aggresome

Biology; Biochemistry

A cytological inclusion in cells that is composed of damaged or mis-folded protein molecules, often following heat stress. Presumably amount of protein in an aggresome is too large to be handled by ...

hairpin loop

Biology; Biochemistry

A region in a single polynucleotide strand containing adjacent complementary sequences that allows the polynucleotide to fold back upon itself and form a double-stranded section, as in the cloverleaf ...

Fresco-Alberts-Doty model

Biology; Biochemistry

A region in a single polynucleotide strand containing adjacent complementary sequences that allows the polynucleotide to fold back upon itself and form a double-stranded section, as in the cloverleaf ...

autoradiography

Biology; Biochemistry

A technique for visualization of radioactivity in histological preparations, paper chromatograms or slab gels from electrophoresis by overlaying the surface with X-ray film and allowing the radiation ...

twisting number (T)

Biology; Biochemistry

A topological property of double-stranded DNA; the number of turns one DNA strand makes around the other; the number of paired bases in a DNA molecule divided by 10; equal to the linking number minus ...

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