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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

β sheet

Biology; Immunology

A β sheet is one of the fundamental structural building blocks of proteins, consisting of adjacent, extended strands of amino acids (β strands) that are bonded together by interactions between ...

gene segments

Biology; Immunology

The V domains of the polypeptide chains of antigen receptors are encoded in sets of gene segments that must first undergo somatic recombination to form a complete V-domain exon. There are three types ...

immunoreceptor tyrosine-based activation motifs

Biology; Immunology

The T and B cell antigen receptors are associated with transmembrane molecules with immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domains. These tyrosine-containing ...

Fab fragments

Biology; Immunology

IgG antibody molecules can be cleaved into three fragments by the enzyme papain. Two of these are identical Fab fragments, so called because they are the Fragment with specific antigen binding. The ...

mast cells

Biology; Immunology

Mast cells are large cells found in connective tissues throughout the body, most abundantly in the submucosal tissues and the dermis. They contain large granules that store a variety of mediator ...

factor B, factor D, factor H, factor I,

Biology; Immunology

Factor B, factor D, factor H, factor I, and factor P are all components of the alternative pathway of complement activation. Factor B plays a role very similar to that of C2b in the classical ...

hypersensitivity reactions

Biology; Immunology

Immune responses to innocuous antigens that lead to symptomatic reactions upon reexposure are called hypersensitivity reactions. These can cause hypersensitivity diseases if they occur repetitively. ...

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