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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

gene targeting

Biology; Immunology

A gene can be specifically disrupted by a technique known as gene targeting or gene knockout. Usually this involves homologous recombination in embryonic stem cells followed by the preparation of ...

immunotoxins

Biology; Immunology

Immunotoxins are antibodies that are chemically coupled to toxic proteins usually derived from plants or microbes. The antibody targets the toxin moiety to the required cells. Immunotoxins are being ...

intracutaneous

Biology; Immunology

Injections can be administered by a number of routes: intracutaneous (intradermal)—entering the skin or dermis; subcutaneous—entering below the skin or dermis; intramuscular—entering the muscle; ...

primary interaction

Biology; Immunology

The binding of antibody molecules to antigen is called a primary interaction, as distinct from secondary interactions in which binding is detected by some associated change such as the precipitation ...

class II-associated invariant chain peptide

Biology; Immunology

The class II-associated invariant chain peptide (CLIP) is a peptide of variable length cleaved from the class II invariant chain by proteases. It remains associated with the MHC class II molecule in ...

polyclonal activation

Biology; Immunology

Antigen activates specific lymphocytes, whereas all mitogens, by definition, activate most or all lymphocytes, a process known as polyclonal activation because it involves multiple clones of diverse ...

antigen display libraries

Biology; Immunology

Both libraries of cDNA clones in expression vectors and bacteriophage libaries encoding random peptide sequences have been used to identify the targets of specific antibodies and, in some cases, of T ...

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