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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
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Immunology
constant region
Biology; Immunology
The constant region (C region) of an immunoglobulin or T-cell receptor is that part of the molecule that is relatively constant in amino acid sequence between different molecules. In an antibody ...
equilibrium dialysis
Biology; Immunology
The affinity of an antibody for its antigen can be determined by equilibrium dialysis, a technique in which antibody in a dialysis bag is exposed to varying amounts of a small antigen able to diffuse ...
capture
Biology; Immunology
Antibodies or antigens can be measured in various capture assays. In these assays, antigens are captured by antibodies bound to plastic (or vice versa). Antibody binding to a plate-bound antigen can ...
indirect Coombs test
Biology; Immunology
The indirect Coombs test is a variation of the direct Coombs test in which an unknown serum is tested for antibodies against normal red blood cells by first mixing the two and then washing out the ...
medulla
Biology; Immunology
The medulla is generally the central or collecting point of an organ. The thymic medulla is the central area of each thymic lobe, rich in bone marrow-derived antigen-presenting cells and the cells of ...
V(D)J recombinase
Biology; Immunology
The enzyme that joins the gene segments of B-cell and T-cell receptor genes is called the V(D)J recombinase. It is made up of several enzymes, but most important are the products of the ...
immunoprecipitation analysis
Biology; Immunology
Soluble proteins, or membrane proteins solubilized in detergents, can be labeled and then detected by immunoprecipitation analysis using specific antibodies. The immunoprecipitated labeled protein is ...