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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
somatic diversification theory
Biology; Immunology
When immunologists discovered that antibodies were variable, they entertained various theories, including the somatic diversification theory that postulated that the genes for immunoglobulin were ...
effector lymphocytes
Biology; Immunology
Effector lymphocytes can mediate the removal of pathogens from the body without the need for further differentiation, as distinct from naive lymphocytes, which must proliferate and differentiate ...
radiation bone marrow chimeras
Biology; Immunology
Radiation bone marrow chimeras are mice that have been heavily irradiated and then reconstituted with bone marrow cells of a different strain of mouse, so that the lymphocytes differ genetically from ...
draining lymph node
Biology; Immunology
The term draining lymph node is used for any lymph node that is downstream of a site of infection and thus receives antigens and microbes from the site via the lymphatic system. Draining lymph nodes ...
tumor-specific transplantation antigens
Biology; Immunology
Tumors transplanted into syngeneic recipients can grow progressively or can be rejected through T-cell recognition of tumor-specific transplantation antigens (TSTA) or tumor rejection antigens. TSTA ...
tyrosine kinase
Biology; Immunology
A tyrosine kinase is an enzyme that specifically phosphorylates tyrosine residues in proteins. They are critical in T- and B-cell activation. The kinases that are critical for B-cell activation are ...
MHC congenic
Biology; Immunology
Various specialized strains of mice are used to explore the role of MHC polymorphism in vivo. These are called MHC congenic, meaning that the mice differ only at the MHC complex, MHC recombinant, ...
