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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

primary follicles

Biology; Immunology

Lymphoid tissues contain lymphoid follicles made up of follicular dendritic cells and B lymphocytes. The primary follicles contain resting B lymphocytes and are the site at which germinal centers ...

graft-versus-host

Biology; Immunology

When mature T lymphocytes are injected into a nonidentical immunoincompetent recipient, they can attack the recipient, causing a graft-versus-host (GVH) reaction; in human patients, mature T cells in ...

enzyme-linked immunosorbent assay

Biology; Immunology

The enzyme-linked immunosorbent assay (ELISA) is a serological assay in which bound antigen or antibody is detected by a linked enzyme that converts a colorless substrate into a colored product. The ...

immune surveillance

Biology; Immunology

It has been proposed that most tumors that arise are detected and eliminated by immune surveillance mediated by lymphocytes specific for tumor antigens. There is little evidence for the efficacy of ...

antibody-dependent cell-mediated cytotoxicity

Biology; Immunology

Antibody-dependent cell-mediated cytotoxicity (ADCC) is the killing of antibody-coated target cells by cells with Fc receptors that recognize the constant region of the bound antibody. Most ADCC is ...

immunogenetics

Biology; Immunology

Immunogenetics was originally the analysis of genetic traits by means of antibodies against genetically polymorphic molecules such as blood group antigens or MHC proteins. Immunogenetics now refers ...

continuous epitopes

Biology; Immunology

Continuous epitopes, or linear epitopes, are antigenic determinants on proteins that are contiguous in the amino acid sequence and therefore do not require the protein to be folded into its native ...

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