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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
interferons
Biology; Immunology
Interferons are cytokines that can induce cells to resist viral replication. Interferon-α (IFN-α) and interferon-β (IFN-β) are produced by leukocytes and fibroblasts, respectively, as well as by ...
major histocompatibility complex
Biology; Immunology
The major histocompatibility complex (MHC) class II proteins are assembled in the endoplasmic reticulum with the invariant chain (Ii), which is involved in shielding the MHC class II molecules from ...
somatic hypermutation,
Biology; Immunology
During B-cell responses to antigen, the V-region DNA sequence undergoes somatic hypermutation, resulting in the generation of variant immunoglobulins, some of which bind antigen with a higher ...
acute lymphoblastic leukemia
Biology; Immunology
Acute lymphoblastic leukemia is a highly aggressive, undifferentiated form of lymphoid malignancy derived from a progenitor cell that is thought to be able to give rise to both T and B lineages of ...
C4b-binding protein
Biology; Immunology
C4b-binding protein can inactivate the classical pathway C3 convertase if it forms on host cells, by displacing C2b from the C4b:C2b complex. It binds to C4b attached to host cells, but cannot bind ...
complement receptors
Biology; Immunology
Complement receptors (CRs) are cell-surface proteins on various cells that recognize and bind complement proteins that have bound an antigen such as a pathogen. Complement receptors on phagocytes ...
cluster of differentiation 45 (CD45)
Biology; Immunology
CD45, or the leukocyte common antigen, is a transmembrane tyrosine phosphatase found on all leukocytes. It is expressed in different isoforms on different cell types, including the different subtypes ...
