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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

contact hypersensitivity reaction

Biology; Immunology

A contact hypersensitivity reaction is a form of delayed-type hypersensitivity in which T cells respond to antigens that are introduced by contact with the skin. Poison ivy hypersensitivity is a ...

E-rosettes

Biology; Immunology

E-rosettes are human T cells that will bind to treated red blood cells from sheep; the many red blood cells bound to each T cell give it the appearance of a rosette and increase its buoyant density ...

calcineurin

Biology; Immunology

The cytosolic serine/threonine phosphatase calcineurin has a crucial role in signaling via the T-cell receptor. The immunosuppressive drugs cyclosporin A and tacrolimus (also known as FK506) form ...

gut-associated lymphoid tissues

Biology; Immunology

The gut-associated lymphoid tissues (GALT) are lymphoid tissues closely associated with the gastrointestinal tract, including the palatine tonsils, Peyer’s patches, and intraepithelial lymphocytes. ...

blood group antigens

Biology; Immunology

Blood group antigens are surface molecules on red blood cells that are detectable with antibodies from other individuals. The major blood group antigens are called ABO and Rh (Rhesus), and are used ...

mannan-binding lectin

Biology; Immunology

The mannan-binding lectin (MBL), also called mannose-binding protein, is an acute-phase protein that binds to mannose residues. It can opsonize pathogens bearing mannose on their surfaces and can ...

leukocyte functional antigens

Biology; Immunology

The leukocyte functional antigens or LFAs, are cell adhesion molecules initially defined with monoclonal antibodies: LFA-1 is a β2 integrin; LFA-2 is a member of the immunoglobulin superfamily, as is ...

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