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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

idiotypic network

Biology; Immunology

Lymphocyte antigen receptors can recognize one another through idiotope–anti-idiotope interactions, forming an idiotypic network of receptors that may be important for the generation and maintenance ...

NK1.1 CD4 T cells

Biology; Immunology

NK1.1 CD4 T cells are a small subset of T cells that express the NK1.1 marker, a molecule normally found on NK cells. NK1.1 T cells also express α:β T-cell receptors of limited diversity and either ...

P-nucleotides

Biology; Immunology

P-nucleotides are nucleotides found in junctions between gene segments of the rearranged V-region genes of antigen receptors. They are an inverse repeat of the sequence at the end of the adjacent ...

immune clearance

Biology; Immunology

When large amounts of antigen are injected into the blood, they are initially removed slowly by normal catabolic processes that also degrade plasma proteins. However, if the antigen elicits an ...

cross-reaction

Biology; Immunology

A cross-reaction is the binding of antibody to an antigen not used to elicit that antibody. Thus, if antibody raised against antigen A also binds antigen B, it is said to cross-react with antigen B. ...

MHC-restricted antigen recognition

Biology; Immunology

MHC-restricted antigen recognition, or MHC restriction, refers to the fact that a given T cell will recognize a peptide antigen only when it is bound to a particular MHC molecule. Normally, as T ...

polymorphonuclear leukocytes

Biology; Immunology

Polymorphonuclear leukocytes are white blood cells with multilobed nuclei and cytoplasmic granules. There are three types of polymorpho-nuclear leukocyte: the neutrophils with granules that stain ...

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