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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
complement receptor 2 CR2
Biology; Immunology
CR2 (CD21) is part of the B-cell co-receptor complex along with CD19 and CD81. It binds to antigens that have various breakdown products of C3, especially C3d, bound to them and, by cross-linking to ...
congenic
Biology; Immunology
Congenic strains of mice are genetically identical at all loci except one. Each strain is generated by the repetitive back-crossing of mice carrying the desired trait onto a strain that provides the ...
C1 inhibitor
Biology; Immunology
C1 inhibitor (C1INH) is a protein that inhibits the activity of activated complement component C1 by binding to and inactivating its C1r:C1s enzymatic activity. It also inhibits other serine ...
CD8 T cells
Biology; Immunology
CD8 T cells are T cells that carry the co-receptor CD8. They recognize antigens, for example viral antigens, that are synthesized in the cytoplasm of a cell. Peptides derived from these antigens are ...
Fcγ receptors
Biology; Immunology
Fcγ receptors, including FcγRI, RII, and RIII, are cell-surface receptors that bind the Fc portion of IgG molecules. Most Fcγ receptors bind only aggregated IgG, allowing them to discriminate bound ...
combinatorial diversity
Biology; Immunology
Antigen receptors manifest two distinct types of combinatorial diversity generated by the combination of separate units of genetic information. Receptor gene segments are joined in many different ...
C1 complex
Biology; Immunology
The C1 complex of complement components comprises one molecule of C1q bound to two molecules each of the zymogens C1r and C1s. C1q initiates the classical pathway of complement activation by binding ...
