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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

neutrophils

Biology; Immunology

Neutrophils, also known as neutrophilic polymorphonuclear leukocytes, are the major class of white blood cell in human peripheral blood. They have a multilobed nucleus and neutrophilic granules. ...

systemic anaphylaxis

Biology; Immunology

Systemic anaphylaxis is the most dangerous form of immediate hypersensitivity reaction. It involves antigen in the bloodstream triggering mast cells all over the body. The activation of these mast ...

δ T-cell receptor

Biology; Immunology

Most T lymphocytes have α:β heterodimeric T-cell receptors, but some bear a distinct γ:δ T-cell receptor composed of different antigen-recognition chains, γ and δ, assembled in a γ:δ heterodimer. ...

purine nucleotide phosphorylase

Biology; Immunology

Purine nucleotide phosphorylase (PNP) deficiency is an enzyme defect that results in severe combined immunodeficiency. This enzyme is important in purine metabolism, and its deficiency causes the ...

immunological ignorance

Biology; Immunology

Immunological ignorance describes a form of self tolerance in which reactive lymphocytes and their target antigen are both detectable within an individual, yet no autoimmune attack occurs. Most ...

clonotypic

Biology; Immunology

A feature unique to individual cells or members of a clone is said to be clonotypic. Thus, a monoclonal antibody that reacts with the receptor on a cloned T-cell line is said to be a clonotypic ...

tec kinase

Biology; Immunology

Activation of the lymphocyte antigen receptors is linked to activation of PLC-γ through members of the Tec kinase family of src-like tyrosine kinases. Other Tec kinases are Btk in B cells, which is ...

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