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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

Fc fragment

Biology; Immunology

IgG antibody molecules can be cleaved into three fragments by the enzyme papain. One of these is the Fc fragment, so-called for Fragment crystallizable. The Fc fragment consists of the C-terminal ...

TUNEL assay

Biology; Immunology

The TUNEL assay (TdT-dependent dUTP–biotin nick end labeling) identifies apoptotic cells in situ by the characteristic fragmentation of their DNA. Biotin-tagged dUTP added to the free 3′ ends of the ...

co-receptor

Biology; Immunology

A co-receptor is a cell-surface protein that increases the sensitivity of the antigen receptor to antigen by binding to associated ligands and participating in signaling for activation. CD4 and CD8 ...

diacylglycerol

Biology; Immunology

Diacylglycerol (DAG) is most commonly released from inositol phospholipids by the action of phospholipase C-γ. Diacylglycerol production is stimulated by the ligation of many receptors and it acts as ...

Wu and Kabat plot

Biology; Immunology

A Wu and Kabat plot, or variability plot, is generated from the amino acid sequences of related proteins by plotting the variability of the sequence against amino acid residue number. Variability is ...

ELISPOT assay

Biology; Immunology

ELISPOT assay is an adaptation of ELISA in which cells are placed over antibodies or antigens attached to a plastic surface. The antigen or antibody traps the cells’ secreted products, which can then ...

immunology

Biology; Immunology

Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in ...

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