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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

anaphylaxis

Biology; Immunology

Immediate hypersensitivity response to antigenic challenge, mediated by IgE and mast cells. It is a life-threatening allergic reaction, caused by the release of pharmacologically active agents.

anergy

Biology; Immunology

A state of antigen-specific nonresponsiveness in which a T or B cell is present but functionally unable to respond to antigen.

ankylosing spondylitis

Biology; Immunology

A chronic inflammatory disease affecting the spine, sacroiliac joints, and large peripheral joints. There is a major genetic predisposition, as revealed by increased incidence in selected families. ...

antibody

Biology; Immunology

Serum protein formed in response to immunization; antibodies are generally defined in terms of their specific binding to the immunizing antigen.

antibody-dependent, cell-mediated cytotoxicity (ADCC)

Biology; Immunology

A phenomenon in which target cells, coated with antibody, are destroyed by specialized killer cells (NK cells and macrophages), which bear receptors for the Fc portion of the coating antibody (Fc ...

antigen

Biology; Immunology

Any foreign material that is specifically bound by antibody or lymphocytes; also used loosely to describe materials used for immunization. Compare with immunogen.

antigen presentation

Biology; Immunology

The display of antigen as peptide fragments bound to MHC molecules on the surface of a cell; T cells recognize antigen only when it is presented in this way.

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