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Molecular biology

Contributors in Molecular biology

Molecular biology

amino acid

Biology; Biochemistry

Usually an α-amino acid, in which a carboxy and an amino (or imino) group are attached to the α-carbon; triple- and single-letter codes are shown: alanine Ala A arginine Arg R asparagine ...

bidirectional PCR amplification of specific alleles (bi-PASA)

Biology; Biochemistry

A method for determination of zygosity. Two sets of primers are used. Of the inner set, primer A is complementary to a point mutation on the coding strand and primer B is complementary to the ...

massively parallel signature sequencing (MPSS)

Biology; Biochemistry

A method for automated identification by sequence and quantitative evaluation of expressed genes, which is unaffected by sequence-dependent variations in hybridization efficiencies. A microbead cDNA ...

scintillation proximity assay (SPA)

Biology; Biochemistry

A method for quantification of a molecule on the basis of its containing a specific ligand. The molecule is labelled with a weakly emitting radioisotope and a ligand, e.g. a ( 3 H)glycoprotein. The ...

polyketide

Biology; Biochemistry

A compound derived from biosynthetic acetyl and/or propionyl units and other building blocks, in which carbonyl carbons condense with a-carbons analogously to the synthesis of fatty acids. They are ...

CATH

Biology; Biochemistry

The acronym for class, architecture, topology, homologous superfamily; a hierarchical system of classification of protein structures named for the highest of the hierarchies: class refers to the ...

polymerase chain reaction (PCR)

Biology; Biochemistry

A technique to amplify a specific region of double-stranded DNA. An excess of two amplimers, oligonucleotide primers complementary to two sequences that flank the region to be amplified, are annealed ...

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