Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

The process by which an intron is excised and exons are religated in the post-transcriptional modification of RNA. The process is effected in vivo by a complex, called a spliceosome, of small nuclear ...

enzyme activity

Biology; Biochemistry

The rate of an enzyme, its activity, may be expressed in several ways, depending on the purity of the enzyme and one's knowledge of its characteristics, e.g. molecular mass and active sites per ...

small molecule library

Biology; Biochemistry

A collection of related structures synthesized for screening for a desired property. The library may by synthesized by parallel, split or spatially addressable synthesis. Parallel synthesis is a ...

Fourier transform infrared spectroscopy (FT-IR)

Biology; Biochemistry

The special case of the application to the infrared spectrum (10 -6 -10 -4 m) of interference optics. To avoid the disadvantage of dispersion/slit optics (the use of a prism or grating to separate ...

funnel concept

Biology; Biochemistry

The new view of the protein folding problem in which the assortment of unfolded polypeptides are considered as an ensemble, the myriad of individual members of which achieve the native form by ...

mismatch repair analysis

Biology; Biochemistry

An assay system for detection of single-base mismatches in a DNA fragment of up to 10 Kb in length, which depends upon an Escherichia coli repair system that detects mismatched bases between a newly ...

self-splicing

Biology; Biochemistry

The activity of the precursor of mature RNA whereby it catalyzes its own (cis>) splicing. Group I introns (examples are Tetrahymena rRNA and hammerhead ribozymes) are self-spliced with the assistance ...