Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

A chaperone machine of a prokaryote mitochondrion or plasmid; a class of molecular chaperones, a complex of proteins which functions to properly fold denatured or improperly folded globular proteins. ...

genetic footprinting

Biology; Biochemistry

An approach to the identification of the function of a large number of putative genes of a micro-organism, such as may have been uncovered by genome sequencing. A transposable element is inserted ...

P:O ratio

Biology; Biochemistry

The ratio of phosphate incorporated into ATP to oxygen atoms reduced to water; a measure of the efficiency of coupling of phosphorylation to oxidation. Based on the now-obsolete chemical coupling ...

sequencing by hybridization

Biology; Biochemistry

A proposed approach to rapid sequencing of genomic DNA. The key tool for analysis is a superchip, a surface over which are attached at minute yet identifiable positions unlabelled oligonucleotide ...

differential hybridization

Biology; Biochemistry

A method for comparison of different organs, or physiological or disease states by the genes that are uniquely expressed in them. The mRNAs of two types of cell to be compared, e.g. normal and cancer ...

end ligation coincident sequence cloning (EL-CSC)

Biology; Biochemistry

A technique for selection of DNA sequences common to two DNA populations. Of the two populations, the one of lowest complexity (or one made least complex by the creation of representations) is used ...

representational difference analysis (RDA)

Biology; Biochemistry

A method for isolation and amplification of DNA sequences that differ between two populations (a subtractive technique); e.g. changes associated with antigenic variation in micro-organisms, ...