11 Terms
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Molecular biology
Industry: Biology
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Molecular biology
mapping
Biology; Biochemistry
The creation of an outline of locations of genetic markers (genes or other polynucleotide sequences) within the structures of the chromosomes. The methodology determines the resolution of the map. ...
Kunkel mutagenesis
Biology; Biochemistry
A method to construct a site-specific mutated gene and to select it away from the wild-type. A strain of E. coli with only weak dUTPase activity has high levels of dUTP and consequently incorporates ...
dUTP system mutagenesis
Biology; Biochemistry
A method to construct a site-specific mutated gene and to select it away from the wild-type. A strain of E. coli with only weak dUTPase activity has high levels of dUTP and consequently incorporates ...
prion
Biology; Biochemistry
A proteinaceous infectious particle which causes one of a number of non-inflammatory, slowly-developing degenerative neurological diseases which are characterized by extracellular plaques, notably ...
hydrogen exchange
Biology; Biochemistry
A method for evaluating secondary and tertiary structure of a polypeptide in solution. The amide hydrogens of the polypeptide backbone slowly exchange with water hydrogens, unless they are ...
Koshland model
Biology; Biochemistry
A sequential model for the basis of co-operativity in multimeric binding proteins, originally presented as a description of oxygen binding to each of the haem groups of the haemoglobin tetramer. ...
KNF model
Biology; Biochemistry
A sequential model for the basis of co-operativity in multimeric binding proteins, originally presented as a description of oxygen binding to each of the haem groups of the haemoglobin tetramer. ...
