Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

A method for detection of a point mutation that neither produces nor destroys a restriction site; intended especially for screening large numbers of individuals. One of the PCR primers is designed so ...

retrotransposon

Biology; Biochemistry

A mobile genetic element composed of repetitive DNA sequences that flank open reading frames, including one that codes for a reverse transcriptase. In contrast to transposons, which in prokaryotes ...

signal recognition particle (SRP)

Biology; Biochemistry

In the synthesis of secretory, endoplasmic reticulum (ER), Golgi apparatus, lysosomal and integral membrane proteins, a ribonucleoprotein that recognizes a signal sequence and prevents further ...

chaperone machine

Biology; Biochemistry

A multi-component system that ensures the proper folding of nascent proteins or their intracellular transport following synthesis; components include chaperones (eukaryotes) or chaperonins (from ...

molecular chaperone

Biology; Biochemistry

Enzymes and other cellular protein complexes that ensure the proper folding of nascent or improperly folded proteins. There are two classes of chaperone: the heat shock protein (hsp) 70 family and ...

electrophoresis

Biology; Biochemistry

A technique that separates charged compounds according to their mobilities in an electric field. In free zone electrophoresis the compounds are in a solution unsupported by any stabilizing matrix. In ...

rolling transcription

Biology; Biochemistry

The synthesis of RNA from a circular DNA template. Some circular DNAs, even without a promoter sequence and without assistance of a primer, may be transcribed to form concatenated circular RNA. If ...