The Environmental Protection Agency approval of a new pesticide for specific uses before it can be sold or distributed in the United States. Under the Federal Insecticide, Fungicide, and Rodenticide Act, the Environmental Protection Agency is responsible for registering (pre-market licensing) pesticides based on scientific evidence that the approved use will result in no unreasonable adverse effects on human health or the environment when applied according to approved label directions. The label on a registered pesticide specifies the legal obligations of the user in terms of uses, timing, and rates of application.