Molecular biology

Molecular biology

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Molecular biology

C-terminal

Biology; Biochemistry

In a polypeptide sequence, that unique residue which is connected to the linear sequence by its amino group, leaving it with a free carboxy group. In practice, the carboxy group of a C-terminal ...

nucleotide

Biology; Biochemistry

A nucleoside with one, two or three phosphate(s) esterified to one of the free hydroxy groups of the sugar moiety, usually the 3'- or 5'-hydroxy group; ribonucleotide if the sugar is D-ribose; ...

nucleoside

Biology; Biochemistry

A purine or pyrimidine base with a sugar attached in a glycosidic linkage; ribonucleoside if the sugar is D-ribose and deoxyribonucleoside if the sugar is D-deoxyribose.

The site where the two polynucleotides of a parent DNA separate during replication. The daughter strands are attached to the two separated polynucleotides that trail away from the fork as it advances ...

oncoprotein

Biology; Biochemistry

The translation product of an oncogene; a regulator of cellular processes, which if the gene is mutated, results in uncontrolled growth (cancer). Oncoproteins may be embedded in the plasma membrane ...

hydropathy plot

Biology; Biochemistry

A graph that shows regions of hydrophobicity or polarity of a protein; a line graph that displays the hydropathy index against the position of each residue of the protein. Each residue is averaged ...

paralogous

Biology; Biochemistry

Descriptive of homologous genes that have duplicated and evolved divergently, e.g. those encoding trypsin, chymotrypsin, elastase and thrombin, which are all serine proteinases and occur together ...